Product Description |
Recombinant FITC-equivalent Human Claudin 18.2 Protein-Nanodisc is expressed from HEK293 with His tag at the N-terminus.It contains Met1-Val261. |
Product Background |
Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. |
Product Category |
Recombinant Protein |
Target |
Claudin 18.2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val261 |
Molecular Weight |
The protein has a predicted MW of 49.10 kDa. |
Activity |
The affinity constant of 6.63 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
N-His |
Fluorophore |
FITC |
Express System |
HEK293 |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
FITC-equivalent Human Claudin 18.2 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-Claudin18.2 Antibody with an affinity constant of 6.63 nM as determined in SPR assay (Biacore T200). |
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