Human ACVR1B/Activin RIB Protein (ALK-HM104)
Catalog: ALK-HM104
Order now get it on
Product Description | Recombinant Human ACVR1B/Activin RIB Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser24-Glu126. |
Product Background |
Activin A receptor type I (ACVR1) encodes for a bone morphogenetic protein type I receptor of the TGFβ receptor superfamily. It is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Moreover, ACVR1 has been extensively studied for its causal role in fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder characterised by progressive heterotopic ossification. ACVR1 is linked to different pathologies, including cardiac malformations and alterations in the reproductive system. |
Product Category |
Recombinant Protein |
Target |
ACVR1B/Activin RIB |
Accession | |
Species |
Human |
Amino Acid Range |
Ser24-Glu126 |
Molecular Weight | The protein has a predicted MW of 12.51 kDa. Due to glycosylation, the protein migrates to 15-25 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
You may also be interested in
View more associated products