Name: Human CD161 Protein (CD1-HM161)
Brand: KactusBio
SKU: CD1-HM161-100UG
Price: 379.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD161, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test). The affinity constant of 78.8 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gln67-Ser225

Catalog #CD1-HM161

Size

100UG

500UG

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Product Description	Recombinant Human CD161 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln67-Ser225.
Product Background	CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and detection of disease after treatment.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	CD161
Synonyms	KLRB1; CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; CD161; Ly59; NKR; NKRP1; NKR-P1; NKRP1ANKR
Accession	Q12918-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln67-Ser225
Molecular Weight	The protein has a predicted MW of 19.6 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD161, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test). The affinity constant of 78.8 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Anti-CD161 Antibody, hFc tag captured on CM5 Chip via Anti-hFc IgG can bind Human CD161, His Tag with an affinity constant of 78.8 nM as determined in SPR assay (Biacore T200).
	Immobilized Human CD161, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD161 Antibody, hFc Tag with the EC50 of 5.3ng/ml determined by ELISA (QC Test).
	Human CD161 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD161 is greater than 95% as determined by SEC-HPLC.