Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: His17-Leu531
Catalog #GP1-HM1BA
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Product Description
 Recombinant Human CD42b/GP1BA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His17-Leu531.
Product Background
 Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.
Product Category
 Recombinant Protein
Target
 CD42b/GP1BA
Synonyms
 GP-Ib alpha; GPIb-alpha; GPIbA; GP1BA; BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; VWDP; BP1BA; MGC34595
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 His17-Leu531
Molecular Weight
 The protein has a predicted MW of 57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test).
Human CD42b on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD42b is greater than 95% as determined by SEC-HPLC.
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