Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
Human CD42b/GP1BA Protein (GP1-HM1BA)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: His17-Leu531
Catalog #GP1-HM1BA
Regular price $300.00
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Product Description

Recombinant Human CD42b/GP1BA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His17-Leu531.

Product Background

Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.

Product Category

Recombinant Protein / Antibody discovery

Protein

CD42b/GP1BA

Synonyms

GP-Ib alpha; GPIb-alpha; GPIbA; GP1BA; BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; VWDP; BP1BA; MGC34595

Accession

Species

Human

Biotinylated

no

Amino Acid Range

His17-Leu531

Molecular Weight

The protein has a predicted MW of 57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test). Immobilized Human CD42b, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA (QC Test).
Human CD42b on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CD42b on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD42b is greater than 95% as determined by SEC-HPLC. The purity of Human CD42b is greater than 95% as determined by SEC-HPLC.

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