Human FGFR2 alpha (IIIb) Protein (FGR-HM1BD)
Human FGFR2 alpha (IIIb) Protein (FGR-HM1BD)
Human FGFR2 alpha (IIIb) Protein (FGR-HM1BD)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human FGFR2 alpha (IIIb), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag with the EC50 of 1.9ng/ml determined by ELISA (QC Test).
  • Amino Acid Range: Arg22-Glu378
Catalog #FGR-HM1BD
Regular price $379.50
/
Size

Order by 4pm ET for delivery on:

Human FGFR2 alpha (IIIb) Protein (FGR-HM1BD) Summary

Product Description

Recombinant Human FGFR2 alpha (IIIb) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg22-Glu378.

Product Background

Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha- isoform, or only IgII and IgIII, referred to as the beta- isoform.

Product Category

Recombinant Protein / Antibody discovery / ADC targets

Human FGFR2 alpha (IIIb) Protein (FGR-HM1BD) Specifications/Details

Protein
FGFR2 alpha (IIIb)
Synonyms
FGF R2a; FGFR2 alpha; KGFR; CD332; BBDS; BEK; BFR-1; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25; FLJ98662
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Arg22-Glu378
Molecular Weight
The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human FGFR2 alpha (IIIb), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag with the EC50 of 1.9ng/ml determined by ELISA (QC Test).
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human FGFR2 alpha (IIIb), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag with the EC50 of 1.9ng/ml determined by ELISA (QC Test). Immobilized Human FGFR2 alpha (IIIb), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FGFR2 alpha (IIIb) Antibody, hFc Tag with the EC50 of 1.9ng/ml determined by ELISA (QC Test).
Human FGFR2 alpha (IIIb) on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. Human FGFR2 alpha (IIIb) on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
Serial dilutions of Anti-FGFR2 alpha (IIIb) Antibody were added into Human FGFR2 alpha (IIIb) , His Tag : Biotinylated Human FGF10, No Tag binding reactioins. Serial dilutions of Anti-FGFR2 alpha (IIIb) Antibody were added into Human FGFR2 alpha (IIIb) , His Tag : Biotinylated Human FGF10, No Tag binding reactioins.
The purity of-Human FGFR2 alpha (IIIb) is greater than 95% as determined by SEC-HPLC. The purity of-Human FGFR2 alpha (IIIb) is greater than 95% as determined by SEC-HPLC.
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Recommended Products

Recently viewed