Name: Human GCGR/Glucagon receptor Protein (GCR-HM20R)
Brand: KactusBio
SKU: GCR-HM20R-100UG
Price: 379.5 USD
Availability: InStock

Human GCGR/Glucagon receptor Protein (GCR-HM20R)

Human GCGR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human GCGR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ala26-Lys136

Catalog #GCR-HM20R

Size

100UG

500UG

Order now, ships by:

[{"id":45057912111326,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"GCR-HM20R-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GCGR\/Glucagon receptor Protein (GCR-HM20R) - 100UG","public_title":"100UG","options":["100UG"],"price":37950,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":45057966801118,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"GCR-HM20R-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GCGR\/Glucagon receptor Protein (GCR-HM20R) - 500UG","public_title":"500UG","options":["500UG"],"price":126500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Human GCGR/Glucagon receptor Protein (GCR-HM20R) Summary

Product Description	Recombinant Human GCGR/Glucagon receptor Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala26-Lys136.
Product Background	The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human GCGR/Glucagon receptor Protein (GCR-HM20R) Specifications/Details

Protein	GCGR/Glucagon receptor
Synonyms	Glucagon receptor; GL-R; GCGR; Glucagon R
Accession	P47871
Species	Human
Biotinylated	no
Amino Acid Range	Ala26-Lys136
Molecular Weight	The protein has a predicted MW of 39.00 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human GCGR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GCGR is greater than 95% as determined by SEC-HPLC.