Name: Human GCGR/Glucagon receptor Protein (GCR-HM20R)
Brand: KactusBio
SKU: GCR-HM20R-100UG
Price: 345.0 USD
Availability: InStock

Human GCGR/Glucagon receptor Protein (GCR-HM20R)

Human GCGR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human GCGR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ala26-Lys136

Catalog #GCR-HM20R

Size

100UG

500UG

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Product Description	Recombinant Human GCGR/Glucagon receptor Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala26-Lys136.
Product Background	The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
Product Category	Recombinant Protein / Antibody discovery

Protein	GCGR/Glucagon receptor
Synonyms	Glucagon receptor; GL-R; GCGR; Glucagon R
Accession	P47871
Species	Human
Biotinylated	no
Amino Acid Range	Ala26-Lys136
Molecular Weight	The protein has a predicted MW of 39.00 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human GCGR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GCGR is greater than 95% as determined by SEC-HPLC.