Human HLA-G Free Heavy Chain Protein (HLG-HE41F)
Catalog: HLG-HE41F
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Product Description | Recombinant Human HLA-G Free Heavy Chain Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(C66S). |
Product Background |
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
Product Category |
Recombinant Protein |
Target |
HLA-G Free Heavy Chain |
Synonyms | HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G |
Allele | HLA-G |
Gene/Protein ID |
P17693-1 |
Species |
Human |
Exact Sequence |
Gly25-Thr305(C66S) |
Molecular Weight | The protein has a predicted MW of 35.5 kDa. The protein migrates to 36-40 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human HLA-G Free Heavy Chain, His Tag at 2ug/ml (100ul/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
E.coli |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 20% Glycerol (pH 8.0). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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