Name: Human IL-37b Protein (ILB-HE037)
Brand: KactusBio
SKU: ILB-HE037-100UG
Price: 315.0 USD
Availability: InStock

Catalog #ILB-HE037

Size

100UG

500UG

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Product Description	Recombinant Human IL-37b Protein is expressed from E.coli without tag.It contains Val46~Asp218.
Product Background	IL-37 is a unique member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune Interleukin-37 (IL-37), a newly described member of IL-1family, functioned as a fundamental inhibitor of innate inflammatory and immune responses. IL-37 has five different isoforms, and IL-37b is the most biologically functional subtype. IL-37b Inhibits PGN Induced Cytokines and Chemokines via the Downregulation of Intracellular Nuclear Factor (NF)-κB, PI3K–Akt, and ERK1/2 Pathways.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-37b
Synonyms	IL-1F7b; IL-HLa; FIL1 zeta; IL-1X; IL-1F7; IL-1H; IL-1H4; IL-1 zeta; IL-1RP1; FIL1Z; IL1F7; IL1H4; IL1RP1
Accession	Q9NZH6-1
Species	Human
Biotinylated	no
Amino Acid Range	Val46~Asp218
Molecular Weight	The protein has a predicted MW of 19.30 kDa same as Bis-Tris PAGE result.
Product Tag	No Tag
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM PB, 150mM NaCl, 2mM DTT (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-37b on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-37b is greater than 90% as determined by SEC-HPLC.