Product Description |
Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396. |
Product Background |
Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate. |
Product Category |
Recombinant Protein |
Target |
MVK |
Synonyms |
MK; LRBP; POROK3; MVLK |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Leu396 |
Molecular Weight |
The protein has a predicted MW of 72.23 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-His-GST, C-Strep-II |
Express System |
Baculovirus-Insect Cells |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 2mM DTT, 10% glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human MVK on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
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