Human MVK Protein (MVK-HB101)
  • Express System: Baculovirus-Insect Cells
  • Product Tag: N-His-GST, C-Strep-II
  • Purity: > 90% as determined by Bis-Tris PAGE
  • Amino Acid Range: Met1-Leu396
Catalog #MVK-HB101
Regular price $300.00
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Product Description
Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396.
Product Background
Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate.
Product Category
Recombinant Protein
Target
MVK
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Leu396
Molecular Weight
The protein has a predicted MW of 72.23 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag
N-His-GST, C-Strep-II
Express System
Baculovirus-Insect Cells
Purity
> 90% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 2mM DTT, 10% glycerol (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human MVK on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

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