Human MVK Protein (MVK-HB101)

  • Express System: Baculovirus-Insect Cells
  • Product Tag: N-His-GST, C-Strep-II
  • Purity: > 90% as determined by Tris-Bis PAGE
  • Exact Sequence: Met1-Leu396

Catalog: MVK-HB101

$300.00
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Product Description Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396.

Product Background

Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate.

Product Category

Recombinant Protein

Target

MVK
Accession

Species

Human

Exact Sequence

Met1-Leu396
Molecular Weight The protein has a predicted MW of 72.23 kDa. The protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Product Tag

N-His-GST, C-Strep-II

Express System

Baculovirus-Insect Cells
Purity > 90% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in 20mM Tris, 500mM NaCl, 2mM DTT, 10% glycerol (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human MVK on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

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