Human Proteinase-activated receptor 1/PAR-1 Protein-VLP (PAR-HM01R)
  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Thr425
Catalog #PAR-HM01R
Regular price $1,210.00
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Product Description

Recombinant Human Proteinase-activated receptor 1/PAR-1 Protein-VLP is expressed from HEK293.It contains Met1-Thr425.

Product Background

Proteinase activated receptors (PAR 1-4) are membrane receptors with a unique way of activation by proteinases like thrombin, trypsin and matrix metalloproteinases which lead to a specific cellular response. PAR-1 was present in adenocarcinomas, melanomas, osteosarcomas, glioblastomas, meningiomas, leukaemias and squamous cell carcinomas. PAR-1 is widely expressed in human tumors suggesting an important role in tumorigenesis and providing potential targets for therapy.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein

Proteinase-activated receptor 1/PAR-1

Synonyms

Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor; F2R; CF2R; PAR1; TR

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Met1-Thr425

Molecular Weight

The protein has a predicted MW of 48.79 kDa.

Activity

Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test). See testing image for detail.

Expression System

HEK293

Purity

> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 150mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test). Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
The purity of Human PAR-1 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human PAR-1 VLP is greater than 95% as determined by SEC-HPLC.

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