Human Proteinase-activated receptor 1/PAR-1 VLP (PAR-HM01R)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
Recomended Products: VLP Control (VLP-HM00C)
Amino Acid Range: Met1-Thr425

Catalog #PAR-HM01R

Price

$1,210.00

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Human Proteinase-activated receptor 1/PAR-1 VLP (PAR-HM01R) Summary

Product Description	Recombinant Human Proteinase-activated receptor 1/PAR-1 VLP is expressed from HEK293.It contains Met1-Thr425 (It may have cross reaction with anti-His antibody).
Product Background	Proteinase activated receptors (PAR 1-4) are membrane receptors with a unique way of activation by proteinases like thrombin, trypsin and matrix metalloproteinases which lead to a specific cellular response. PAR-1 was present in adenocarcinomas, melanomas, osteosarcomas, glioblastomas, meningiomas, leukaemias and squamous cell carcinomas. PAR-1 is widely expressed in human tumors suggesting an important role in tumorigenesis and providing potential targets for therapy.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein	Proteinase-activated receptor 1/PAR-1
Synonyms	Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor; F2R; CF2R; PAR1; TR
Accession	P25116
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Thr425
Molecular Weight	The protein has a predicted MW of 48.79 kDa.
Activity	Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 150mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
	The purity of Human PAR-1 VLP is greater than 95% as determined by SEC-HPLC.

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