• Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
  • Negative Control: VLP Control (VLP-HM00C)
  • Amino Acid Range: Met1-Thr425
Catalog #PAR-HM01R
Price
Regular price $1,21000
Regular price Sale price $1,21000
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Size
Avantor VWR Fisher Scientific

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Human Proteinase-activated receptor 1/PAR-1 VLP (PAR-HM01R) Summary

Product Description

 Recombinant Human Proteinase-activated receptor 1/PAR-1 VLP is expressed from HEK293.It contains Met1-Thr425 (It may have cross reaction with anti-His antibody).

Product Background

 Proteinase activated receptors (PAR 1-4) are membrane receptors with a unique way of activation by proteinases like thrombin, trypsin and matrix metalloproteinases which lead to a specific cellular response. PAR-1 was present in adenocarcinomas, melanomas, osteosarcomas, glioblastomas, meningiomas, leukaemias and squamous cell carcinomas. PAR-1 is widely expressed in human tumors suggesting an important role in tumorigenesis and providing potential targets for therapy.

Human Proteinase-activated receptor 1/PAR-1 VLP (PAR-HM01R) Specifications/Details

Protein
 Proteinase-activated receptor 1/PAR-1
Synonyms
 Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor; F2R; CF2R; PAR1; TR
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Thr425
Molecular Weight
 The protein has a predicted MW of 48.79 kDa.
Activity
 Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 150mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test). Immobilized Human PAR-1 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PAR-1 Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test).
The purity of Human PAR-1 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human PAR-1 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...