• Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Met1-Lys366
Catalog #SED-HM107
Price
Regular price $33000
Regular price Sale price $33000
/
Size
Avantor VWR Fisher Scientific

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Human SETD7-Protein (SED-HM107) Summary

Product Description

 Recombinant Human SETD7-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366.

Product Background

 SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs.

Human SETD7-Protein (SED-HM107) Specifications/Details

Protein
 SETD7
Synonyms
 KIAA1717; KMT7; SET7; SET9; SET7/9
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Lys366
Molecular Weight
 The protein has a predicted MW of 41.68 kDa. The protein migrates to 47-50 kDa based on Bis-Tris PAGE result.
Product Tag
 N-His
Fluorophore
 Unconjugated
Expression System
 E.coli
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human SETD7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human SETD7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human SETD7-is greater than 95% as determined by SEC-HPLC. The purity of Human SETD7-is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...