Human SETD7-Protein (SED-HM107)
Human SETD7-Protein (SED-HM107)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Met1-Lys366
Catalog #SED-HM107
Regular price $300.00
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Product Description
Recombinant Human SETD7-Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366.
Product Background
SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs.
Product Category
Recombinant Protein
Target
SETD7
Synonyms
KIAA1717; KMT7; SET7; SET9; SET7/9
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Lys366
Molecular Weight
The protein has a predicted MW of 41.68 kDa. The protein migrates to 47-50 kDa based on Bis-Tris PAGE result.
Product Tag
N-His
Express System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human SETD7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human SETD7-is greater than 95% as determined by SEC-HPLC.

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