Name: Human Tau K18 Protein (TAU-HEK18)
Brand: KactusBio
SKU: TAU-HEK18-100UG
Price: 270.0 USD
Availability: InStock

Express System: E.coli
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Tau K18, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Etalanetug, hFc Tag with the EC50 of 1.1ng/ml determined by ELISA.
Amino Acid Range: Gln244-Glu372

Catalog #TAU-HEK18

Size

100UG

500UG

Order by 4pm ET for delivery on:

Human Tau K18 Protein (TAU-HEK18) Summary

Product Description	Recombinant Human Tau K18 Protein is expressed from E.coli without tag.It contains Gln244-Glu372.
Product Background	As a major microtubule-associated protein, tau plays an important role in promoting microtubule assembly and stabilizing microtubules. In Alzheimer's disease (AD) and other tauopathies, the abnormally hyperphosphorylated tau proteins are aggregated into paired helical filaments and accumulated in the neurons with the form of neurofibrillary tangles. An imbalanced regulation in protein kinases and protein phosphatases is the direct cause of tau hyperphosphorylation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human Tau K18 Protein (TAU-HEK18) Specifications/Details

Protein	Tau K18
Synonyms	PHF-tau; MAPT; MAPTL; MTBT1; TAU; Tau-F; Tau-4; 2N4R
Accession	P10636-8
Species	Human
Biotinylated	no
Amino Acid Range	Gln244-Glu372
Molecular Weight	The protein has a predicted MW of 13.68 kDa. The protein migrates to 17-20 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Tau K18, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Etalanetug, hFc Tag with the EC50 of 1.1ng/ml determined by ELISA.
Product Tag	No Tag
Fluorophore	Unconjugated
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 25mM HEPES, 1M NaCl, 10% Glycerol, 1mM TCEP (pH 7.2).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Tau K18, No Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Etalanetug, hFc Tag with the EC50 of 1.1ng/ml determined by ELISA.
	Human Tau K18 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Tau K18 is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

Finding available proteins...

Loading...