Mouse GIP Protein (GIP-MM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Glu22-Gln85

Catalog: GIP-MM101

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Product Description Recombinant Mouse GIP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Gln85.

Product Background

The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals.

Product Category

Recombinant Protein

Target

GIP
Synonyms GIP; Incretin
Accession

Species

Mouse

Exact Sequence

Glu22-Gln85
Molecular Weight The protein has a predicted MW of 8.7 kDa. Due to glycosylation, the protein migrates to 13-18 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse GIP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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