Name: Mouse TREM2 Protein (TRM-MM101)
Brand: KactusBio
SKU: TRM-MM101-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Mouse TREM2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Leu19-Ser171

Catalog #TRM-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse TREM2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu19-Ser171.
Product Background	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2- consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia.
Product Category	Recombinant Protein / Antibody discovery

Protein	TREM2
Synonyms	PLOSL2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c
Accession	Q99NH8-1
Species	Mouse
Biotinylated	no
Amino Acid Range	Leu19-Ser171
Molecular Weight	The protein has a predicted MW of 17.9 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse TREM2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse TREM2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-TREM2 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA (QC Test).
	Mouse TREM2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.