SARS PLpro/papain-like protease Protein (SAR-VE101)

  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Glu1541-Tyr1859

Catalog: SAR-VE101

$315.00
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Product Description Recombinant SARS PLpro/papain-like protease Protein is expressed from E.coli with His tag at the C-terminus.It contains Glu1541-Tyr1859.

Product Background

The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Product Category

Recombinant Protein

Target

PLpro/papain-like protease

Gene/Protein ID

AAX16193.1

Species

SARS

Exact Sequence

Glu1541-Tyr1859
Molecular Weight The protein has a predicted MW of 36.91 kDa same as Tris-Bis PAGE result.

Product Tag

C-His

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in 50 mM Tris, 0.1 % Tween, 150mM NaCl (pH 9.0).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SARS PLpro on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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