Product Description |
Recombinant SARS PLpro/papain-like protease Protein is expressed from E.coli with His tag at the C-terminus.It contains Glu1541-Tyr1859. |
Product Background |
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
PLpro/papain-like protease |
Synonyms |
Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro |
Accession |
|
Species |
SARS |
Biotinylated |
no |
Amino Acid Range |
Glu1541-Tyr1859 |
Molecular Weight |
The protein has a predicted MW of 36.91 kDa same as Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 50 mM Tris, 0.1 % Tween, 150mM NaCl (pH 9.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed