SARS PLpro/papain-like protease Protein (SAR-VE101)
SARS PLpro/papain-like protease Protein (SAR-VE101)
  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Glu1541-Tyr1859
Catalog #SAR-VE101
Regular price $315.00
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Product Description

Recombinant SARS PLpro/papain-like protease Protein is expressed from E.coli with His tag at the C-terminus.It contains Glu1541-Tyr1859.

Product Background

The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Product Category

Recombinant Protein / Antibody discovery

Protein

PLpro/papain-like protease

Synonyms

Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro

Accession

Species

SARS

Biotinylated

no

Amino Acid Range

Glu1541-Tyr1859

Molecular Weight

The protein has a predicted MW of 36.91 kDa same as Bis-Tris PAGE result.

Product Tag

C-His

Expression System

E.coli

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 50 mM Tris, 0.1 % Tween, 150mM NaCl (pH 9.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SARS PLpro on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. SARS PLpro on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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