Making difficult targets

discovery-ready

Proteins, membrane targets, and enzymes engineered for reliable therapeutic discovery

We make 4000+ difficult biological targets accessible for therapeutic research...

...across a catalog spanning recombinant proteins, membrane targets, immune complexes, and enzymes.

We make 4000+ <strong>difficult biological targets</strong> accessible for therapeutic research...
catalog products

Produced & Tested In-House

Designed, expressed, and verified by us. Quality proteins from end to end.

Tailored Expression Systems

Tailored Expression Systems

Proteins tested in 8-16 various expression conditions to determine the optimal settings.

High Purity & Bioactivity

High Purity & Bioactivity

Rigorous quality control testing for purity and bioactivity using HPLC, SPR, ELISA, etc.

Next-Day Shipping from Boston, MA

Next-Day Shipping from Boston, MA

Catalog products shipped next-day from our inventory center in Boston, MA.

Browse Products by Application

Target Antigens for Drug Discovery

Bioactive target antigens for drug discovery campaigns.
Proteins for Drug Discovery

Gene Editing Products

GMP-Grade gene editing enzymes and AAV Titration ELISA Kits.
Gene Editing Enzymes

RNA Enzymes

Full portfolio of GMP-grade mRNA production enzymes.
RNA Production Enzymes

MHC Tetramers & Monomers

MHC-peptide complexes and peptide-ready MHCs.
MHC Complexes

Cell Therapy Products

CAR-T Targets, Laminin 521, Cytokines, & more.
Cell Therapy Proteins

Multi-Pass Transmembrane Proteins

VLP-Displayed Proteins

Full-length, mammalian expressed membrane proteins displayed on virus-like particles (VLPs) for enhanced immunogenicity

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Nanodisc-Displayed Proteins

Detergent-free extraction copolymer nanodiscs displaying full-length membrane proteins in their native conformation

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MHC Monomers & Tetramers

MHC-Peptide Complexes

MHC-peptide

MHC-peptide

MHC Monomers & Tetramers from mammalian & E. coli expression systems

Peptide-ready MHC

Peptide-ready MHC

Load your own peptide in-house for a custom monomer or tetramer

Biotinylation or fluorescent label

Biotinylated MHC

Biotinylated MHC monomers or tetramers for TCR screening and more

Fluorescent MHC

Fluorescent MHC

Identify antigen-specific T Cells using FACS

MHC Complexes

GMP Gene Editing Enzymes

GMP Gene Editing Enzymes

Cas9 Protein

Off-the-shelf wild-type Cas9 protein with NLS optimization, batch consistency, and high editing activity.

AccuBase® Base Editor

First commercially available base editor. Off-the-shelf editor engineered for near-zero off-target effects and high editing activity

Drug Discovery Collections

Immune Checkpoint Proteins
Immune Checkpoint Proteins
CD3 Proteins
CD3 Proteins
Fc Receptor Proteins
Fc Receptor Proteins
Integrin Proteins
Integrin Proteins
Chimeric Antigen Receptor T Cell Therapy (CAR-T) Proteins
Chimeric Antigen Receptor T Cell Therapy (CAR-T) Proteins
Cadherin Proteins
Cadherin Proteins

Trending Products

AAV Titration ELISA Kits

Quantification of AAV capsids for serotypes 2, 5, 6, 8, or 9 with high specificity to individual AAV serotypes, high sensitivity, and a broad linear range.
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<p>AAV Titration ELISA Kits</p>

AccuBase® Base Editor

GMP-Grade. Precise DNA cytosine base editor with minimal off-target effects, creating C->T mutations for gene knockout without DNA breaks.
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<p>AccuBase® Base Editor</p>

CD19 Proteins

Mammalian-expressed human CD19 proteins with high monomer rates. Various spcies and fluorescent options. In-stock catalog products.
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<p>CD19 Proteins</p>

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CD44v9: Exploring a Novel Target and Clinical Progress in ADC-Resistant Tumors

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PTK7: Exploring a Promising Target for Cancer Therapeutics

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