Human CCR8 Protein-Nanodisc (CR8-HM1N29)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Human CCR8 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA (QC Test). The affinity constant of 53.40 pM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Met1-Leu355
Catalog #CR8-HM1N29
Regular price $1,485.00
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Product Description

Recombinant Human CCR8 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu355.

Product Background

CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc
Protein
CCR8
Synonyms
CCR-8; CMKBRL2; CKR-L1; GPR-CY6; GPRCY6; TER1; CCR8; CKRL1; CMKBR8; CD198; ChemR1; CKR-L1; CY6; TER-1; CDw198
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Leu355
Molecular Weight
The protein has a predicted MW of 42.60 kDa.
Activity
Immobilized Human CCR8 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA (QC Test). The affinity constant of 53.40 pM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human CCR8 nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-CCR8 Antibody, hFc Tag with an affinity constant of 53.40 pM as determined in SPR assay (Biacore T200). Human CCR8 nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-CCR8 Antibody, hFc Tag with an affinity constant of 53.40 pM as determined in SPR assay (Biacore T200).
Immobilized Human CCR8 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA (QC Test). Immobilized Human CCR8 Nanodisc, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA (QC Test).
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