• Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Human CXCR4 VLP at 5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CXCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA.
  • Amino Acid Range: Met1-Ser352
Catalog #CXC-HM04VB
Price
Regular price $1,76500
Regular price Sale price $1,76500
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Size
Avantor VWR Fisher Scientific

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Biotinylated Human CXCR4 VLP (CXC-HM04VB) Summary

Product Description

Recombinant Biotinylated Biotinylated Human CXCR4 VLP is expressed from HEK293.It contains Met1-Ser352.

Product Background

CXC chemokine receptor type 4 (CXCR4) is a member of the G protein-coupled receptors (GPCRs) superfamily and is specific for CXC chemokine ligand 12 (CXCL12, also known as SDF-1), which makes CXCL12/CXCR4 axis. CXCR4 interacts with its ligand, triggering downstream signaling pathways that influence cell proliferation chemotaxis, migration, and gene expression.

Biotinylated Human CXCR4 VLP (CXC-HM04VB) Specifications/Details

Protein
CXCR4
Synonyms
CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; LESTR; LAP-3; NPYRL; NPYR; NPY3R; SDF-1 receptor; CD184; D2S201E; HSY3RR;;CXCR4; LAP3; SDF1 receptor
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Met1-Ser352
Molecular Weight
The target protein has a predicted MW of 42.68 kDa.
Activity
Immobilized Biotinylated Human CXCR4 VLP at 5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CXCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA.
Fluorophore
Biotin-labeled
Expression System
HEK293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Human CXCR4 VLP at 5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CXCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA. Immobilized Biotinylated Human CXCR4 VLP at 5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-CXCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA.
The purity of Biotinylated Human CXCR4 VLP is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human CXCR4 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...