• Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Val20-Met433
Catalog #GCC-MM401B
Price
Regular price $577.50
Regular price Sale price $577.50
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Size
Avantor VWR Fisher Scientific

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Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein (GCC-MM401B) Summary

Product Description

 Recombinant Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Val20-Met433.

Product Background

 Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.

Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein (GCC-MM401B) Specifications/Details

Protein
 GUCY2C/Guanylyl cyclase C
Synonyms
 Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL;EC4.6.1; GUC2CEC4.6.1.2
Accession
Species
 Mouse
Biotinylated
 yes
Amino Acid Range
 Val20-Met433
Molecular Weight
 The protein has a predicted MW of 50.01 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Mouse GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Mouse GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Mouse GUCY2C is greater than 90% as determined by SEC-HPLC. The purity of Biotinylated Mouse GUCY2C is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...