• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
  • Amino Acid Range: Leu33-Lys531
Catalog #PGF-CM1RB
Price
Regular price $33000
Regular price Sale price $33000
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus PDGF R beta/CD140b Protein (PGF-CM1RB) Summary

Product Description

 Recombinant Cynomolgus PDGF R beta/CD140b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Lys531.

Product Background

 Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.

Cynomolgus PDGF R beta/CD140b Protein (PGF-CM1RB) Specifications/Details

Protein
 PDGF R beta/CD140b
Synonyms
 PDGF-R-beta; PDGFR-beta; PDGFRB; PDGF R beta; PDGFR-2; PDGFR-β;PDGFR2;PDGFR-b
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Leu33-Lys531
Molecular Weight
 The protein has a predicted MW of 57.49 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
Cynomolgus PDGF R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus PDGF R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus PDGF R beta is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus PDGF R beta is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...