• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 90% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln21-Asp224
Catalog #SAP-MM201
Price
Regular price $26400
Regular price Sale price $26400
/
Size
Avantor VWR Fisher Scientific

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Mouse Pentraxin 2/SAP Protein (SAP-MM201) Summary

Product Description

 Recombinant Mouse Pentraxin 2/SAP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln21-Asp224.

Product Background

 Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases.

Mouse Pentraxin 2/SAP Protein (SAP-MM201) Specifications/Details

Protein
 Pentraxin 2/SAP
Synonyms
 SAP; APCS; MGC88159; Pentraxin 2; PTX2
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Gln21-Asp224
Molecular Weight
 The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 90% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl, 0.05% CHAPS, 5mM CaCl2, 100mM L-arginine (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse Pentraxin 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. Mouse Pentraxin 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
The purity of Mouse Pentraxin 2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse Pentraxin 2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...