Biotinylated Human FGF10 Protein (Primary Amine Labeling) (FGF-HE010B)
|Recombinant Biotinylated Human FGF10 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Gln38-Ser208.
|Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
|The protein has a predicted MW of 19.3 kDa same as Tris-Bis PAGE result.
|The affinity constant of 147.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
|> 90% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
|Less than 1EU per ug by the LAL method.
|Shipped at ambient temperature.
|Lyophilized from 0.22um filtered solution in 20mM Tris,150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
|Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
|Stability And Storage
|Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.