Name: Biotinylated Human KIR2DL3 Protein (KIR-HM4L3B)
Brand: KactusBio
SKU: KIR-HM4L3B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human KIR2DL3 Protein (KIR-HM4L3B)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: His22-His245

Catalog #KIR-HM4L3B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
Product Background	KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Product Category	Recombinant Protein

Target	KIR2DL3
Synonyms	cl-6; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; NKAT; NKAT2; NKAT-2; NKAT2A; NK-receptor; p58; NKAT2GL183; CD158b; CD158B2; GL183; KIR-023GB; KIR2DS5; NKAT2B
Accession	P43628
Species	Human
Biotinylated	yes
Amino Acid Range	His22-His245
Molecular Weight	The protein has a predicted MW of 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Biotinylated Human KIR2DL3-on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Biotinylated Human KIR2DL3 is greater than 95% as determined by SEC-HPLC.

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