Biotinylated Human KIR2DL3 Protein (KIR-HM4L3B)
Biotinylated Human KIR2DL3 Protein (KIR-HM4L3B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: His22-His245
Catalog #KIR-HM4L3B
Regular price $525.00
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Product Description

Recombinant Biotinylated Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.

Product Background

KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Product Category

Recombinant Protein / Antibody discovery

Protein

KIR2DL3

Synonyms

cl-6; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; NKAT; NKAT2; NKAT-2; NKAT2A; CD158b; CD158B2; GL183; KIR2DS5; NKAT2B

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

His22-His245

Molecular Weight

The protein has a predicted MW of 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human KIR2DL3-on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. Biotinylated Human KIR2DL3-on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Biotinylated Human KIR2DL3 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human KIR2DL3 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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