Name: Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B)
Brand: KactusBio
SKU: SIG-HM205B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B)

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Glu17-Thr434

Catalog #SIG-HM205B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Siglec-5/CD170 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu17-Thr434.
Product Background	Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.
Product Category	Recombinant Protein

Target	Siglec-5/CD170
Synonyms	CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2
Accession	O15389
Species	Human
Biotinylated	yes
Amino Acid Range	Glu17-Thr434
Molecular Weight	The protein has a predicted MW of 73.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Biotinylated Human Siglec-5 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

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