Name: Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B)
Brand: KactusBio
SKU: SIG-HM205B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B)

Biotinylated Human Siglec-5 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Glu17-Thr434
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Catalog #SIG-HM205B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B) Summary

Product Description	Recombinant Biotinylated Human Siglec-5/CD170 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu17-Thr434.
Product Background	Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling) (SIG-HM205B) Specifications/Details

Protein	Siglec-5/CD170
Synonyms	CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2
Accession	O15389
Species	Human
Biotinylated	yes
Amino Acid Range	Glu17-Thr434
Molecular Weight	The protein has a predicted MW of 73.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc (IgG1)
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.