Cynomolgus BST2 Protein (BST-CM202)
Catalog: BST-CM202
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Product Description | Recombinant Cynomolgus BST2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile49-Ser163. |
Product Background |
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor. |
Product Category |
Recombinant Protein |
Target |
BST2 |
Accession | |
Species |
Cynomolgus |
Amino Acid Range |
Ile49-Ser163 |
Molecular Weight | The protein has a predicted MW of 13.78 kDa. Due to glycosylation, the protein migrates to 15-30 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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