Cynomolgus Fc gamma RIII/CD16 Protein (FGR-CM1R3)

  • Express System: Expi293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.251 μM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Gly17-Gln208

Catalog: FGR-CM1R3

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Product Description Recombinant Cynomolgus Fc gamma RIII/CD16 Protein is expressed from Expi293 with His tag at the C-terminal.It contains Gly17-Gln208.
Product Category Recombinant Protein
Target Fc gamma RIII/CD16
Synonyms IgG Fc receptor III; Fc-gamma RIII; FcRIII; FCGR3; CD16; CD16A; FCG3; FcgRIII; FCR-10; FCRIIIA; IGFR3; IMD20
Gene/Protein ID Q8SPW2-1
Species Cynomolgus
Exact Sequence Gly17-Gln208
Molecular Weight The protein has a predicted MW of 23.1 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
Activity The affinity constant of 0.251 μM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag C-His
Express System Expi293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Rituximab captured on CM5 Chip via Protein A can bind Cynomolgus Fc gamma RIII, His Tag with an affinity constant of 0.251 μM as determined in SPR assay (Biacore T200).
The purity of Cynomolgus Fc gamma RIII is greater than 95% as determined by SEC-HPLC.
Cynomolgus Fc gamma RIII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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