Cynomolgus HPX Protein (HPX-CM101)
Cynomolgus HPX Protein (HPX-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asn24-Tyr462
Catalog #HPX-CM101
Regular price $315.00
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Product Description

Recombinant Cynomolgus HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn24-Tyr462.

Product Background

Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.

Product Category

Recombinant Protein / Antibody discovery

Protein

HPX

Synonyms

Hemopexin;Hpx;Hpxn

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Asn24-Tyr462

Molecular Weight

The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in 20mM MES, 150mM NaCl (pH 6.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 20mM MES, 150mM NaCl (pH 6.0).
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus HPX on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus HPX on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus HPX is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus HPX is greater than 95% as determined by SEC-HPLC.

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