Cynomolgus Transthyretin/Prealbumin Protein (TSR-CM101)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gly21-Glu147

Catalog: TSR-CM101

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Product Description Recombinant Cynomolgus Transthyretin/Prealbumin Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gly21-Glu147.

Product Background

 Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.

Product Category

 Recombinant Protein

Target

 Transthyretin/Prealbumin

Gene/Protein ID

 Q8HXW1

Species

 Cynomolgus

Exact Sequence

 Gly21-Glu147
Molecular Weight The protein has a predicted MW of 14.80 kDa. Due to glycosylation, the protein migrates to 16-20 kDa based on Tris-Bis PAGE result.

Product Tag

 N-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Cynomolgus Transthyretin is greater than 95% as determined by SEC-HPLC.
Cynomolgus Transthyretin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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