Name: Cynomolgus VSIG4 Protein (VSG-CM104)
Brand: KactusBio
SKU: VSG-CM104-100UG
Price: 315.0 USD
Availability: InStock

Catalog #VSG-CM104

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100UG

500UG

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Product Description	Recombinant Cynomolgus VSIG4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg25-Ala288.
Product Background	VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
Product Category	Recombinant Protein / Antibody discovery

Protein	VSIG4
Synonyms	CRIg; Z39IG; VSIG4
Accession	A0A7N9D9P6
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Arg25-Ala288
Molecular Weight	The protein has a predicted MW of 30.16 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus VSIG4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus VSIG4 is greater than 95% as determined by SEC-HPLC.