Cynomolgus VSIG4 Protein (VSG-CM104)
Cynomolgus VSIG4 Protein (VSG-CM104)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg25-Ala288
Catalog #VSG-CM104
Regular price $315.00
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Product Description
Recombinant Cynomolgus VSIG4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg25-Ala288.
Product Background
VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
Product Category
Recombinant Protein
Target
VSIG4
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Arg25-Ala288
Molecular Weight
The protein has a predicted MW of 30.16 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus VSIG4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus VSIG4 is greater than 95% as determined by SEC-HPLC.

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