Human APOE4/Apolipoprotein E Protein (APO-HM202)
Human APOE4/Apolipoprotein E Protein (APO-HM202)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Lys19-His317
Catalog #APO-HM202
Regular price $270.00
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Product Description

Recombinant Human APOE4/Apolipoprotein E Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Lys19-His317.

Product Background

Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).

Product Category

Recombinant Protein

Protein

APOE4/Apolipoprotein E

Synonyms

Apolipoprotein E; Apo-E; APOE; apolipo E; APOE4

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Lys19-His317

Molecular Weight

The protein has a predicted MW of 61.6 kDa. Due to glycosylation, the protein migrates to 63-67 kDa based on Bis-Tris PAGE result.

Product Tag

N-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS, 2mM DTT, 5mM CHAPS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human APOE4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human APOE4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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