Name: Human APOE4/Apolipoprotein E Protein (APO-HM202)
Brand: KactusBio
SKU: APO-HM202-100UG
Price: 297.0 USD
Availability: InStock

Human APOE4/Apolipoprotein E Protein (APO-HM202)

Human APOE4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: N-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Lys19-His317

Catalog #APO-HM202

Size

100UG

500UG

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Product Description	Recombinant Human APOE4/Apolipoprotein E Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Lys19-His317.
Product Background	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	APOE4/Apolipoprotein E
Synonyms	Apolipoprotein E; Apo-E; APOE; apolipo E; APOE4
Accession	AAB59397.1
Species	Human
Biotinylated	no
Amino Acid Range	Lys19-His317
Molecular Weight	The protein has a predicted MW of 61.6 kDa. Due to glycosylation, the protein migrates to 63-67 kDa based on Bis-Tris PAGE result.
Product Tag	N-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 2mM DTT, 5mM CHAPS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.