Product Description |
Recombinant Human CD79B Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala29-Asp159. |
Product Background |
CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. |
Product Category |
Recombinant Protein |
Target |
CD79B |
Synonyms |
B29; CD79b molecule; CD79B; IGB; IGBAGM6; Ig-beta; Ig-β |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala29-Asp159 |
Molecular Weight |
The protein has a predicted MW of 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human CD79B, hFc Tag at 1ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Anti-CD79B Antibody, hFc Tag with the EC50 of 12.3ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Human CD79B, hFc Tag at 1ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Anti-CD79B Antibody, hFc Tag with the EC50 of 12.3ng/ml determined by ELISA (QC Test). |
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Human CD79B on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. |
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The purity of Human CD79B is greater than 95% as determined by SEC-HPLC. |
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