Name: Human CDH17/Cadherin 17 Domain 2 Protein (CDH-HM32D)
Brand: KactusBio
SKU: CDH-HM32D-100UG
Price: 390.0 USD
Availability: InStock

Human CDH17/Cadherin 17 Domain 2 Protein (CDH-HM32D)

Human CDH17 Domain 2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-mFc
Purity: >95% as determined by Bis-Tris PAGE
Amino Acid Range: Ser129-Pro244

Catalog #CDH-HM32D

Size

100UG

500UG

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Product Description	Recombinant Human CDH17/Cadherin 17 Domain 2 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ser129-Pro244.
Product Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category	Recombinant Protein / Antibody discovery

Protein	CDH17/Cadherin 17 Domain 2
Synonyms	Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1;
Accession	Q12864
Species	Human
Biotinylated	no
Amino Acid Range	Ser129-Pro244
Molecular Weight	The protein has a predicted MW of 39.25 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Product Tag	C-mFc
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.； -80°C for 3 months after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.