Human Claudin 18.2 VLP (CLD-HM0P37)
SKU: CLD-HM0P37-100UG
Human Claudin 18.2 VLP (CLD-HM0P37)
SKU: CLD-HM0P37-100UG
Product Description |
Human Claudin 18.2 VLP is expressed from HEK293. It contains Met1-Val261 (It may have cross reaction with anti-His antibody). |
Product Background |
Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP | ADC targets |
Protein |
Claudin 18.2 |
Synonyms |
CLDN18; CLDN18.2; Claudin-18.2; Claudin18.2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val261 |
Molecular Weight |
The target protein has a predicted MW of 29 kDa. |
Activity |
Immobilized Human Claudin 18.2 VLP at 5ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 11.0 ng/ml determined by ELISA (QC Test). |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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