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Non-biotinylated Human CLEC2D Protein (CLD-HM52D) Summary
Product Description |
Recombinant Human CLEC2D Protein is expressed from HEK293 with hFc (IgG1) tag and Avi tag at the N-Terminus.It contains Arg60-Val191. |
Product Background |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART). |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Non-biotinylated Human CLEC2D Protein (CLD-HM52D) Specifications/Details
Protein |
CLEC2D |
Synonyms |
C-type lectin domain family 2 member D;Lectin-like NK cell receptor;Lectin-like transcript 1;LLT-1;CLAX;LLT1;OCIL;CLEC2D |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Arg60-Val191 |
Molecular Weight |
The protein has a predicted MW of 59.1 kDa. Due to glycosylation, the protein migrates to 72-78 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-hFc (IgG1)-Avi |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human CLEC2D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human CLEC2D is greater than 90% as determined by SEC-HPLC. |
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