Human CLEC7A Protein (CLE-HM27A)

Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.

Human CLEC7A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human CLEC7A is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
Amino Acid Range: Thr66-Met201

Catalog #CLE-HM27A

Price

$297⁰⁰

Size

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Human CLEC7A Protein (CLE-HM27A) Summary

Product Description

Recombinant Human CLEC7A Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Thr66-Met201.

Product Background

Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders.

Human CLEC7A Protein (CLE-HM27A) Specifications/Details

Protein	CLEC7A
Synonyms	Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4
Accession	Q9BXN2-2
Species	Human
Biotinylated	no
Amino Acid Range	Thr66-Met201
Molecular Weight	The protein has a predicted MW of 41.79 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
Product Tag	N-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
	Human CLEC7A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CLEC7A is greater than 95% as determined by SEC-HPLC.