Product Description |
Recombinant Human CLEC7A Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr66-Met201. |
Product Background |
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders. |
Product Category |
Recombinant Protein |
Target |
CLEC7A |
Synonyms |
Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Thr66-Met201 |
Molecular Weight |
The protein has a predicted MW of 41.79 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human CLEC7A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human CLEC7A is greater than 95% as determined by SEC-HPLC. |
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