Human CLEC7A Protein (CLE-HM27A)
Human CLEC7A Protein (CLE-HM27A)
Human CLEC7A Protein (CLE-HM27A)
  • Express System: HEK293
  • Product Tag: N-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Activity: Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
  • Amino Acid Range: Thr66-Met201
Catalog #CLE-HM27A
Regular price $297.00
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Size
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Human CLEC7A Protein (CLE-HM27A) Summary

Product Description

Recombinant Human CLEC7A Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Thr66-Met201.

Product Background

Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human CLEC7A Protein (CLE-HM27A) Specifications/Details

Protein
CLEC7A
Synonyms
Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Thr66-Met201
Molecular Weight
The protein has a predicted MW of 41.79 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
Product Tag
N-hFc (IgG1)

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA. Immobilized Human CLEC7A, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CLEC7A Antibody, hFc Avi Tag with the EC50 of 5.0ng/ml determined by ELISA.
Human CLEC7A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CLEC7A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CLEC7A is greater than 90% as determined by SEC-HPLC. The purity of Human CLEC7A is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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