Product Description |
Recombinant Human FSHB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asn19-Glu129. |
Product Background |
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. |
Product Category |
Recombinant Protein |
Target |
FSHB |
Synonyms |
FSH-beta; FSH-B; FSHB; Follitropin;FSH-β |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asn19-Glu129 |
Molecular Weight |
The protein has a predicted MW of 39.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human FSHB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human FSHB is greater than 95% as determined by SEC-HPLC. |
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