Human FSHB Protein (FSH-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Asn19-Glu129

Catalog: FSH-HM201

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Product Description Recombinant Human FSHB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asn19-Glu129.

Product Background

Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins.

Product Category

Recombinant Protein

Target

FSHB
Synonyms FSH-beta; FSH-B; FSHB; Follitropin

Gene/Protein ID

P01225

Species

Human

Exact Sequence

Asn19-Glu129
Molecular Weight The protein has a predicted MW of 39.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Human FSHB is greater than 95% as determined by SEC-HPLC.
Human FSHB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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