Human Hepcidin/HAMP Protein (HEP-HE601)
  • Express System: E.coli
  • Product Tag: N-GST
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Asp60-Thr84
  • Other Available Proteins:
    Loading...
Catalog #HEP-HE601
Regular price $330.00
/
Size

Order by 4pm ET for delivery on:

Human Hepcidin/HAMP Protein (HEP-HE601) Summary

Product Description

Recombinant Human Hepcidin/HAMP Protein is expressed from E.coli with GST tag at the N-Terminus.It contains Asp60-Thr84.

Product Background

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human Hepcidin/HAMP Protein (HEP-HE601) Specifications/Details

Protein
Hepcidin/HAMP
Synonyms
Hamp1; Hepc; Hepc1; HFE2B; LEAP1; LEAP-1; PLTR
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Asp60-Thr84
Molecular Weight
The protein has a predicted MW of 29.08 kDa same as Bis-Tris PAGE result.
Product Tag
N-GST

Fluorophore

Unconjugated
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in 50mM Tris-HCl, 150mM NaCl, 2mM DTT (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human Hepcidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Hepcidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Recommended Products

Recently viewed