Human Hepcidin/HAMP Protein (HEP-HE601)

  • Express System: E.coli
  • Product Tag: N-GST
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Asp60-Thr84

Catalog: HEP-HE601

$300.00
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Product Description Recombinant Human Hepcidin/HAMP Protein is expressed from E.coli with GST tag at the N-Terminus.It contains Asp60-Thr84.

Product Background

Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.

Product Category

Recombinant Protein

Target

Hepcidin/HAMP
Synonyms Hamp1; Hepc; Hepc1; HFE2B; LEAP1; LEAP-1; PLTR

Gene/Protein ID

P81172

Species

Human

Exact Sequence

Asp60-Thr84
Molecular Weight The protein has a predicted MW of 29.08 kDa same as Tris-Bis PAGE result.

Product Tag

N-GST

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in 50mM Tris-HCl, 150mM NaCl, 2mM DTT (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human Hepcidin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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