Product Description |
Recombinant Human ICAM-3/CD50 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln30-His485. |
Product Background |
ICAM-3 interacts with LFA1, and is involved in the intercellular adhesion of leukocytes as well as in the mainenance of cell survival. ICAM-3 expression induces cancer cell proliferation, and an increase in ICAM-3 expression can contribute to cancer progression. |
Product Category |
Recombinant Protein |
Target |
ICAM-3/CD50 |
Synonyms |
Intercellular adhesion molecule 3; ICAM3; CDw50; ICAM-R; CD50 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln30-His485 |
Molecular Weight |
The protein has a predicted MW of 50.54 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human ICAM-3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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