Human KIR2DL2 Protein (KIR-HM4L2)
Human KIR2DL2 Protein (KIR-HM4L2)
Human KIR2DL2 Protein (KIR-HM4L2)
Human KIR2DL2 Protein (KIR-HM4L2)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: His22-His245
Catalog #KIR-HM4L2
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Product Description
 Recombinant Human KIR2DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
Product Background
 KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
Product Category
 Recombinant Protein
Target
 KIR2DL2
Synonyms
 Killer cell immunoglobulin-like receptor 2DL2；CD158 antigen-like family member B1；MHC class I NK cell receptor；NKAT-6；p58 NK receptor CL-43；CD158b1；KIR2DL2；CD158B1；NKAT6
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 His22-His245
Molecular Weight
 The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human KIR2DL2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human KIR2DL2 is greater than 95% as determined by SEC-HPLC.
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