Human KIR2DL2 Protein (KIR-HM4L2)
Human KIR2DL2 Protein (KIR-HM4L2)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: His22-His245
Catalog #KIR-HM4L2
Regular price $210.00
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Product Description
Recombinant Human KIR2DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
Product Background
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.
Product Category
Recombinant Protein
Target
KIR2DL2
Synonyms
NKAT-6;p58 NK receptor CL-43;CD158b1;KIR2DL2;CD158B1;NKAT6
Accession
Species
Human
Biotinylated
no
Amino Acid Range
His22-His245
Molecular Weight
The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human KIR2DL2 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human KIR2DL2 is greater than 95% as determined by SEC-HPLC.

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