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Human LAMP5 Protein (LAM-HM105) Summary
Product Description |
Recombinant Human LAMP5 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu30-Glu235. |
Product Background |
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. LAMP5 deficiency led to a larger intensity-dependent increase of wave I, II and V peak amplitude of auditory brainstem response. LAMP5 plays a pivotal role in sensorimotor processing in the brainstem and spinal cord. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human LAMP5 Protein (LAM-HM105) Specifications/Details
Protein |
LAMP5 |
Synonyms |
BAD-LAMP; LAMP-5; BADLAMP; C20orf103; dJ1119D9.3; UNC-43 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu30-Glu235 |
Molecular Weight |
The protein has a predicted MW of 24.17 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human LAMP5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human LAMP5 is greater than 95% as determined by SEC-HPLC. |
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