• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 90% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA.
  • Amino Acid Range: Gln45-Ser833
Catalog #LIF-HM20R
Price
Regular price $825.00
Regular price Sale price $825.00
/
Size
Avantor VWR Fisher Scientific

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Human LIF R/CD118 Protein (LIF-HM20R) Summary

Product Description

 Recombinant Human LIF R/CD118 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln45-Ser833.

Product Background

 The leukemia inhibitory factor receptor (LIF-R) subunit is a component of cell-surface receptor complexes for the multifunctional cytokines, LIF, cardiotrophin-1, ciliary neurotrophic factor, and human oncostatin M. The structure of the human LIF-R gene is similar to that of the mouse gene. The transmembrane receptor is encoded by 19 exons.

Human LIF R/CD118 Protein (LIF-HM20R) Specifications/Details

Protein
 LIF R/CD118
Synonyms
 FLJ99923; SJS2; STWS; SWS; LIFR; CD118; FLJ98106
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gln45-Ser833
Molecular Weight
 The protein has a predicted MW of 116.1 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA.
Product Tag
 C-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 90% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCL, 200mM L-arginine, 5mM DTT.
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA. Immobilized Human LIF, No Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human LIF R, hFc Tag with the EC50 of 66.8ng/ml determined by ELISA.
Human LIF R on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. Human LIF R on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
Other Available Proteins:
Finding available proteins...