Human LILRB5/CD85c/LIR-8 Protein (LIL-HM4B5)
Human LILRB5/CD85c/LIR-8 Protein (LIL-HM4B5)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Arg18-His456
Catalog #LIL-HM4B5
Regular price $315.00
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Product Description
Recombinant Human LILRB5/CD85c/LIR-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg18-His456.
Product Background
LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.
Product Category
Recombinant Protein
Target
LILRB5/CD85c/LIR-8
Synonyms
CD85C ; LIR-8; LIR8
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Arg18-His456
Molecular Weight
The protein has a predicted MW of 49.9 kDa. Due to glycosylation, the protein migrates to 67-72 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human LILRB5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LILRB5 is greater than 95% as determined by SEC-HPLC.
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