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Human MICA*010:01:06 Protein (MIC-HM102) Summary
Product Description |
Recombinant Human MICA*010:01:06 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Glu24-Thr309. |
Product Background |
MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human MICA*010:01:06 Protein (MIC-HM102) Specifications/Details
Protein |
MICA |
Synonyms |
C5NT78; MICA; MICA*010:01:06 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu24-Thr309 |
Molecular Weight |
The protein has a predicted MW of 34.57 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human MICA*010:01:06 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human MICA*010:01:06 is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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