Human Pentraxin 2/SAP Protein (SAP-HM201)
Human Pentraxin 2/SAP Protein (SAP-HM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: His20-Val223
Catalog #SAP-HM201
Regular price $240.00
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Product Description

Recombinant Human Pentraxin 2/SAP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His20-Val223.

Product Background

Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases.

Product Category

Recombinant Protein / Antibody discovery

Protein

Pentraxin 2/SAP

Synonyms

SAP; APCS; MGC88159; Pentraxin 2; PTX2

Accession

Species

Human

Biotinylated

no

Amino Acid Range

His20-Val223

Molecular Weight

The protein has a predicted MW of 50 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA. Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA.
Human Pentraxin 2/SAP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human Pentraxin 2/SAP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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