Human Pentraxin 2/SAP Protein (SAP-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: His20-Val223

Catalog: SAP-HM201

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Product Description Recombinant Human Pentraxin 2/SAP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His20-Val223.

Product Background

Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases.

Product Category

Recombinant Protein

Target

Pentraxin 2/SAP
Synonyms SAP; APCS; MGC88159; Pentraxin 2; PTX2
Accession

Species

Human

Amino Acid Range

His20-Val223
Molecular Weight The protein has a predicted MW of 50 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 54.5ng/ml determined by ELISA.
Human Pentraxin 2/SAP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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