Human Pentraxin 2/SAP Protein (SAP-HM201)
Catalog: SAP-HM201
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Product Description | Recombinant Human Pentraxin 2/SAP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His20-Val223. |
Product Background |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. |
Product Category |
Recombinant Protein |
Target |
Pentraxin 2/SAP |
Synonyms | SAP; APCS; MGC88159; Pentraxin 2; PTX2 |
Gene/Protein ID |
P02743 |
Species |
Human |
Exact Sequence |
His20-Val223 |
Molecular Weight | The protein has a predicted MW of 50 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human Pentraxin 2, hFc Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-Pentraxin 2 Antibody, hFc Tag with the EC50 58.2ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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