Product Description |
Recombinant Mouse APLN Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val23-Phe77. |
Product Background |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages. Additionally, due to the widespread distribution of the CVD, more effective therapeutic strategies need to be developed to overcome the related complications. |
Product Category |
Recombinant Protein |
Target |
APLN |
Synonyms |
Apelin；APJ endogenous ligand；APEL |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Val23-Phe77 |
Molecular Weight |
The protein has a predicted MW of 33 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS, 200mM Arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse APLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse APLN is greater than 95% as determined by SEC-HPLC. |
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