Name: Mouse Clusterin Protein (CLN-MM101)
Brand: KactusBio
SKU: CLN-MM101-100UG
Price: 297.0 USD
Availability: InStock

Catalog #CLN-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse Clusterin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu22-Glu448.
Product Background	Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.
Product Category	Recombinant Protein / Antibody discovery

Protein	Clusterin
Synonyms	Clusterin; Apo-J; Clustrin; SGP-2; Msgp-2; CLU; AAG4; APOJ; CLI; KUB1; SP-40; TRPM2; CLI; KUB1;
Accession	Q06890
Species	Mouse
Biotinylated	no
Amino Acid Range	Glu22-Glu448
Molecular Weight	The protein has a predicted MW of 50.4 kDa. Due to autocatalytic cleavage, the protein migrates to 35-40 kDa and 43-50 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse Clusterin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Clusterin is greater than 95% as determined by SEC-HPLC.