Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 0.92 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ser20-Arg686
Catalog #SIG-CM122
Regular price $270.00
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Product Description

Recombinant Rhesus macaque Siglec-2/CD22 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-Arg686.

Product Background

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets

Protein

Siglec-2/CD22

Synonyms

CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814

Accession

Species

Rhesus macaque

Biotinylated

no

Amino Acid Range

Ser20-Arg686

Molecular Weight

The protein has a predicted MW of 76.14 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.92 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Anti-Siglec-2 Antibody captured on CM5 Chip via Protein A can bind Rhesus macaque siglec-2, His Tag with an affinity constant of 0.92 uM as determined in SPR assay (Biacore T200). Anti-Siglec-2 Antibody captured on CM5 Chip via Protein A can bind Rhesus macaque siglec-2, His Tag with an affinity constant of 0.92 uM as determined in SPR assay (Biacore T200).
Rhesus macaque Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Rhesus macaque Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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