Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)

Catalog #SIG-CM122

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$297.00

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Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122) Summary

Product Description	Recombinant Rhesus macaque Siglec-2/CD22 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-Arg686.
Product Background	CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets

Protein	Siglec-2/CD22
Synonyms	CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814
Accession	EHH29920.1
Species	Rhesus macaque
Biotinylated	no
Amino Acid Range	Ser20-Arg686
Molecular Weight	The protein has a predicted MW of 76.14 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 8% trehalose (pH 7.4).
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Rhesus macaque Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

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