Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
Rhesus macaque Siglec-2/CD22 Protein (SIG-CM122)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 0.92 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ser20-Arg686
Catalog #SIG-CM122
Regular price $270.00
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Product Description
Recombinant Rhesus macaque Siglec-2/CD22 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-Arg686.
Product Background
CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Product Category
Recombinant Protein
Target
Siglec-2/CD22
Accession
Species
Rhesus macaque
Biotinylated
no
Amino Acid Range
Ser20-Arg686
Molecular Weight
The protein has a predicted MW of 76.14 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 0.92 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Anti-Siglec-2 Antibody captured on CM5 Chip via Protein A can bind Rhesus macaque siglec-2, His Tag with an affinity constant of 0.92 uM as determined in SPR assay (Biacore T200).
Rhesus macaque Siglec-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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