Name: Human GLP-1R Protein (GLP-HM30R)
Brand: KactusBio
SKU: GLP-HM30R-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Arg24-Glu139

Catalog #GLP-HM30R

Size

100UG

500UG

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Product Description	Recombinant Human GLP-1R Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Arg24-Glu139.
Product Background	Glucagon-like peptide-1 (GLP-1) is produced by the gut, stimulates insulin secretion from the pancreatic β-cells, and inhibits glucagon secretion from the α-cells. The GLP-1 receptor (GLP-1R) agonists are used in the treatment of type 2 diabetes (T2DM).
Product Category	Recombinant Protein / Antibody discovery

Protein	GLP-1R
Synonyms	GLP1R; GLP-1-R; GLP-1R;
Accession	P43220
Species	Human
Biotinylated	no
Amino Acid Range	Arg24-Glu139
Molecular Weight	The protein has a predicted MW of 39.20 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-mFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA.
	Human GLP-1R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GLP-1R is greater than 95% as determined by SEC-HPLC.