Human GLP-1R Protein (GLP-HM30R)

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Arg24-Glu139

Catalog: GLP-HM30R

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Human GLP-1R Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Arg24-Glu139.
Product Background	Glucagon-like peptide-1 (GLP-1) is produced by the gut, stimulates insulin secretion from the pancreatic β-cells, and inhibits glucagon secretion from the α-cells. The GLP-1 receptor (GLP-1R) agonists are used in the treatment of type 2 diabetes (T2DM).
Product Category	Recombinant Protein

Target	GLP-1R
Accession	P43220
Species	Human
Amino Acid Range	Arg24-Glu139
Molecular Weight	The protein has a predicted MW of 39.20 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-mFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA.
	The purity of Human GLP-1R is greater than 95% as determined by SEC-HPLC.
	Human GLP-1R on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.