Human GLP-1R Protein (GLP-HM30R)
Human GLP-1R Protein (GLP-HM30R)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Arg24-Glu139
Catalog #GLP-HM30R
Regular price $315.00
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Product Description
Recombinant Human GLP-1R Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Arg24-Glu139.
Product Background
Glucagon-like peptide-1 (GLP-1) is produced by the gut, stimulates insulin secretion from the pancreatic β-cells, and inhibits glucagon secretion from the α-cells. The GLP-1 receptor (GLP-1R) agonists are used in the treatment of type 2 diabetes (T2DM).
Product Category
Recombinant Protein
Target
GLP-1R
Synonyms
GLP1R; GLP-1-R; GLP-1R;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Arg24-Glu139
Molecular Weight
The protein has a predicted MW of 39.20 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-mFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human GLP-1R, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 17.0ng/ml determined by ELISA.
Human GLP-1R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human GLP-1R is greater than 95% as determined by SEC-HPLC.

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