Human GLP-1R Protein (GLP-HM30R)

  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human GLP-1R, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Arg24-Glu139

Catalog: GLP-HM30R

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Product Description Recombinant Human GLP-1R Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Arg24-Glu139.

Product Background

Glucagon-like peptide-1 (GLP-1) is produced by the gut, stimulates insulin secretion from the pancreatic β-cells, and inhibits glucagon secretion from the α-cells. The GLP-1 receptor (GLP-1R) agonists are used in the treatment of type 2 diabetes (T2DM).

Product Category

Recombinant Protein

Target

GLP-1R

Gene/Protein ID

P43220

Species

Human

Exact Sequence

Arg24-Glu139
Molecular Weight The protein has a predicted MW of 39.20 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human GLP-1R, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-mFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human GLP-1R, mFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA.
The purity of Human GLP-1R is greater than 95% as determined by SEC-HPLC.
Human GLP-1R on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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